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PF-HT8-E

The fully automated multifunctional molecular detection instrument can analyze interactions between various biomolecules in real time, providing high-quality biological information on kinetics, affinity, antibody screening, and concentration determination without the need for labeling.

8 parallel detection channels, with a single load capacity of 2 x 96-well plates, significantly improving kinetics/affinity screening throughput.

Affinity testing for 8 samples in <10 minutes, kinetics screening for 96 samples in as fast as 5 minutes.

Lower detection limit of 150 Da, suitable for small molecule fragment drug screening and fine analysis such as molecular fishing.

Baseline noise <0.3RU, drift <0.03RU/min, ensuring stable and reliable data.

Supports various applications including kinetics, epitope identification, and paired screening.

Specifications

Detection channels: 8

Automation level: Fully automatic

Capacity: 2 x 96-well plates

Detection applications: Kinetics/Affinity characterization, Kinetics/Affinity screening, Small molecule interaction analysis, Fragment drug screening, Epitope identification, Paired screening, Molecular fishing

Sample incubation: /

ELISA detection: /

Association constant (ka): Protein: 10¹~10⁷ M⁻¹·s⁻¹; Small molecule: 10³~5×10⁷ M⁻¹·s⁻¹

Dissociation constant (kd): 10⁻⁶~10⁻¹ s⁻¹

Affinity range (KD): 10 pM~1 mM

Lower detection limit: 150 Da

Detection time: Affinity testing for 8 samples in <10 min, up to 12h real-time kinetics binding experiments; kinetics screening for up to 96 samples simultaneously with minimum analysis time of 5 min, data sorted by binding signal intensity

Baseline noise (RMS): <0.3 RU

Baseline drift: <0.03 RU/min